PinnedZongmei Gao·Jun 12, 2025Evaluating the Quality of GWAS Results： Primarily Depends on the QQ PlotToday, I want to talk about how to evaluate the quality of GWAS (Genome-Wide Association Study) results. For each trait, GWAS can be…A response icon1A response icon1
Zongmei Gao·Oct 29From One SNP to One Candidate Gene: How GWAS, eQTL, and TWAS Fit TogetherA practical guide to moving from a statistical association to a defensible biological hypothesis — without confusing proximity…
Zongmei Gao·Oct 2710 Signaling Pathways Every Bioinformatician Should KnowA practical guide to PI3K, MAPK, NF-kB, Wnt, TGF-beta, JAK/STAT, AMPK, p53, Notch, and Hippo — plus how to analyze them without…A response icon1A response icon1
Zongmei Gao·Oct 27ENCODE, GENCODE, ClinVar, GTEx: A Beginner’s Map of Genomics TermsHow to tell databases, assays, atlases, annotations, and QTLs apart — and choose the right one for your biological question
Zongmei Gao·Oct 26Doublet Detection in Single-Cell RNA-seq: A Practical scDblFinder WorkflowWhen to run it, what “sample” really means, and how to avoid deleting real biology
Zongmei Gao·Oct 23Ten Classic Signaling Pathways Every Biologist Should RecognizeA practical guide to GPCR, MAPK, PI3K, JAK-STAT, NF-kB, TGF-beta, Wnt, Notch, Hedgehog, and Hippo signaling
Zongmei Gao·Oct 22Gene Expression Regulation: From the Lac Operon to Chromatin, Enhancers, and RNAiA beginner-friendly map of how cells decide when, where, and how strongly a gene should be expressed
Zongmei Gao·Oct 20How to Read qPCR Results: Ct Values, Melt Curves, and 2^-ΔΔCt Without GuessingA practical workflow for deciding whether the run worked, calculating relative expression, and troubleshooting curves before they become…
Zongmei Gao·Oct 19AI Virtual Cells Are Not Digital Cells — YetWhat these models actually predict, why perturbation data matters, and how to read the first benchmarks without the hype
Zongmei Gao·Oct 17Single-Cell Metabolism Without Four Separate PipelinesA practical, no-code workflow for pathway…Single-cell RNA sequencing can tell us which metabolic genes are expressed in each cell. Turning that expression matrix into a metabolic…
